Sodium Citrate Sigma-Grade Chemical – Ultra-Purity Buffering & Sequestrant for Advanced Industrial & Pharmaceutical Formulations
Our Sodium Citrate (Tri Sodium Citrate, Na₃C₆H₅O₇, CAS 68-04-2) is engineered to meet Sigma-grade analytical precision, offering ≥99.9% purity with sub-ppm impurity control via multi-stage ion-exchange purification. As a trusted Chinese supplier with 25 years of global export experience, we deliver 22,000+ MT annually to 70+ countries, specializing in pharmaceutical-grade, food-safe, and industrial-strength variants tailored for R&D labs, drug manufacturers, and heavy industries.


Key Product Advantages
- Analytical-Grade Purity:
99.9–99.95% assay (HPLC-validated) with ≤0.1 ppm arsenic, ≤0.3 ppm lead, and ≤5 ppm chloride.
Sigma-compliant specs: Meets USP, EP, JP, and ACS reagent standards for laboratory and clinical use.
- Thermal & Solubility Stability:
Solubility: 820 g/L (25°C) for instant dissolution in aqueous and polar organic solvents.
pH (5% aq. sol.): 80–85°C stable at 8.2–8.8, ideal for heat-sensitive formulations.
- Traceability: Lot-specific CoA with NMR, ICP-MS, and laser diffraction particle analysis (D50 ≤ 15 μm).
- Eco-Conscious Production: 100% recycled water usage and closed-loop citrate recovery (ISO 14046-certified).
Technical Specifications
|
Parameter |
Specification |
Test Method |
|
Purity (HPLC) |
≥99.9% |
USP <34> + ACS Reagent Grade |
|
Arsenic (As) |
≤0.1 ppm |
ICP-MS (EPA 200.8, sub-ppt) |
|
Lead (Pb) |
≤0.3 ppm |
GD-MS (ASTM E1979) |
|
Chloride (Cl⁻) |
≤5 ppm |
Potentiometric Titration (ASTM D512) |
|
Solubility (25°C, g/100 mL) |
820 ± 5 |
Gravimetric Analysis (ISO 787-3) |
|
pH (5% aq. sol.) |
8.2–8.8 |
pH Electrode (NIST-traceable) |
|
Endotoxin (EU/g) |
<0.05 EU/g |
LAL Assay (USP <85>, pyrogen-free) |
Export-Grade Packaging Solutions
- Pharma/Laboratory Grade:
1 kg glass bottles (amber-tinted, nitrogen-flushed) for light-sensitive reagents.
5 kg HDPE drums (UN-certified, tamper-evident seals) for bulk lab use.
- Food/Industrial Grade:
25 kg multi-layer paper bags (PE-lined, UV-resistant) for food additive storage.
1,500 kg FIBC bulk bags (food-grade PP with anti-static liners) for mining/water treatment.
- Labeling: Multilingual SDS (24 languages) + UN hazard class 8 labeling (corrosive) + GHS-compliant symbols.
Industry-Specific Applications
1.Pharmaceuticals & Biotech:
Buffering agent in IV fluids: Maintains pH 7.4±0.1 for 24+ hours (compliant with USP <791>).
Anticoagulant in blood collection tubes: Prevents clotting with 1:9 citrate-to-blood ratios (FDA 510(k)-cleared).
Chelator in radiopharmaceuticals: Enhances imaging contrast by 200% vs. standard EDTA (ISO 11137-validated).
2.Food & Beverage:
Emulsifier in cheese: Reduces syneresis by 60% in processed cheeses (FDA GRAS-approved).
Antioxidant in meat: Extends shelf life by 45% in vacuum-packed beef (E331iii-compliant).
3.Water Treatment:
Sequestrant in cooling towers: Prevents scale formation at 5 ppm dosage (reduces maintenance costs by 50%).
Coagulant aid in wastewater: Removes 98% of heavy metals (compliant with EPA 40 CFR Part 503).
4.Metalworking & Mining:
Corrosion inhibitor in ferrous pickling: Protects steel from hydrogen embrittlement (ASTM B117-tested).
Flotation reagent in mineral processing: Increases ore recovery by 15% in copper extraction.
Factory Competitiveness
- Capacity: 30,000 MT/year with 99.98% lot-to-lot consistency via AI-driven process control.
- Quality: Quadruple ISO certifications (9001, 13485, 22000, 14001); audited by Merck, Roche.
- Sustainability:
100% renewable energy (solar + wind) for production.
98% of waste repurposed into animal feed additives and biodegradable detergents.
Why Choose Our Sodium Citrate Sigma-Grade?
- 50% Cost Advantage: Direct factory pricing vs. European/US Sigma-Aldrich equivalents.
- Regulatory Flexibility: Quadruple-certified (USP/EP/JP/ACS + Kosher/Halal) for global R&D and manufacturing.
- Tailored Formulations:
Anhydrous Sodium Citrate (99.99% purity) for moisture-sensitive applications.
Liquid Concentrates (60% w/w) for instant formulation without dust hazards.
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